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A general approach for stabilizing nanobodies for intracellular expression
Conventional antibodies and their derived fragments are difficult to deploy against intracellular targets in live cells, due to their bulk and structural complexity. Nanobodies provide an alternative modality, with well-documented examples of intracellular expression. Despite their promise as intrac...
Autores principales: | Dingus, John G, Tang, Jonathan CY, Amamoto, Ryoji, Wallick, Grace K, Cepko, Constance L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683787/ https://www.ncbi.nlm.nih.gov/pubmed/36416528 http://dx.doi.org/10.7554/eLife.68253 |
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