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T cell receptor convergence is an indicator of antigen-specific T cell response in cancer immunotherapies

T cells are potent at eliminating pathogens and playing a crucial role in the adaptive immune response. T cell receptor (TCR) convergence describes T cells that share identical TCRs with the same amino acid sequences but have different DNA sequences due to codon degeneracy. We conducted a systematic...

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Detalles Bibliográficos
Autores principales: Pan, Mingyao, Li, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683788/
https://www.ncbi.nlm.nih.gov/pubmed/36350695
http://dx.doi.org/10.7554/eLife.81952