Transcriptome-wide association study and eQTL colocalization identify potentially causal genes responsible for human bone mineral density GWAS associations

Genome-wide association studies (GWASs) for bone mineral density (BMD) in humans have identified over 1100 associations to date. However, identifying causal genes implicated by such studies has been challenging. Recent advances in the development of transcriptome reference datasets and computational...

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Detalles Bibliográficos
Autores principales: Al-Barghouthi, Basel Maher, Rosenow, Will T, Du, Kang-Ping, Heo, Jinho, Maynard, Robert, Mesner, Larry, Calabrese, Gina, Nakasone, Aaron, Senwar, Bhavya, Gerstenfeld, Louis, Larner, James, Ferguson, Virginia, Ackert-Bicknell, Cheryl, Morgan, Elise, Brautigan, David, Farber, Charles R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683789/
https://www.ncbi.nlm.nih.gov/pubmed/36416764
http://dx.doi.org/10.7554/eLife.77285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683789/
https://www.ncbi.nlm.nih.gov/pubmed/36416764
http://dx.doi.org/10.7554/eLife.77285

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