Structural and functional insights of the human peroxisomal ABC transporter ALDP

Adrenoleukodystrophy protein (ALDP) is responsible for the transport of very-long-chain fatty acids (VLCFAs) and corresponding CoA-esters across the peroxisomal membrane. Dysfunction of ALDP leads to peroxisomal metabolic disorder exemplified by X-linked adrenoleukodystrophy (ALD). Hundreds of ALD-c...

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Detalles Bibliográficos
Autores principales: Jia, Yutian, Zhang, Yanming, Wang, Wenhao, Lei, Jianlin, Ying, Zhengxin, Yang, Guanghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683791/
https://www.ncbi.nlm.nih.gov/pubmed/36374178
http://dx.doi.org/10.7554/eLife.75039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683791/
https://www.ncbi.nlm.nih.gov/pubmed/36374178
http://dx.doi.org/10.7554/eLife.75039

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