Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in monkeys

Pediatric SARS-CoV-2 vaccines are needed that elicit immunity directly in the airways as well as systemically. Building on pediatric parainfluenza virus vaccines in clinical development, we generated a live-attenuated parainfluenza-virus-vectored vaccine candidate expressing SARS-CoV-2 prefusion-sta...

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Detalles Bibliográficos
Autores principales: Le Nouën, Cyril, Nelson, Christine E., Liu, Xueqiao, Park, Hong-Su, Matsuoka, Yumiko, Luongo, Cindy, Santos, Celia, Yang, Lijuan, Herbert, Richard, Castens, Ashley, Moore, Ian N., Wilder-Kofie, Temeri, Moore, Rashida, Walker, April, Zhang, Peng, Lusso, Paolo, Johnson, Reed F., Garza, Nicole L., Via, Laura E., Munir, Shirin, Barber, Daniel L., Buchholz, Ursula J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684001/
https://www.ncbi.nlm.nih.gov/pubmed/36423629
http://dx.doi.org/10.1016/j.cell.2022.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684001/
https://www.ncbi.nlm.nih.gov/pubmed/36423629
http://dx.doi.org/10.1016/j.cell.2022.11.006

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