Phenotypic plasticity and genetic control in colorectal cancer evolution

Genetic and epigenetic variation, together with transcriptional plasticity, contribute to intratumour heterogeneity(1). The interplay of these biological processes and their respective contributions to tumour evolution remain unknown. Here we show that intratumour genetic ancestry only infrequently...

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Detalles Bibliográficos
Autores principales: Househam, Jacob, Heide, Timon, Cresswell, George D., Spiteri, Inmaculada, Kimberley, Chris, Zapata, Luis, Lynn, Claire, James, Chela, Mossner, Maximilian, Fernandez-Mateos, Javier, Vinceti, Alessandro, Baker, Ann-Marie, Gabbutt, Calum, Berner, Alison, Schmidt, Melissa, Chen, Bingjie, Lakatos, Eszter, Gunasri, Vinaya, Nichol, Daniel, Costa, Helena, Mitchinson, Miriam, Ramazzotti, Daniele, Werner, Benjamin, Iorio, Francesco, Jansen, Marnix, Caravagna, Giulio, Barnes, Chris P., Shibata, Darryl, Bridgewater, John, Rodriguez-Justo, Manuel, Magnani, Luca, Sottoriva, Andrea, Graham, Trevor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684078/
https://www.ncbi.nlm.nih.gov/pubmed/36289336
http://dx.doi.org/10.1038/s41586-022-05311-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684078/
https://www.ncbi.nlm.nih.gov/pubmed/36289336
http://dx.doi.org/10.1038/s41586-022-05311-x

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