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Pharmacological targeting of glutamatergic neurons within the brainstem for weight reduction

Food intake and body weight are tightly regulated by neurons within specific brain regions, including the brainstem, where acute activation of dorsal raphe nucleus (DRN) glutamatergic neurons expressing the glutamate transporter Vglut3 (DRN(Vglut3)) drive a robust suppression of food intake and enha...

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Detalles Bibliográficos
Autores principales: Schneeberger, Marc, Brice, Nicola L., Pellegrino, Kyle, Parolari, Luca, Shaked, Jordan T., Page, Keith J., Marchildon, François, Barrows, Douglas W., Carroll, Thomas S., Topilko, Thomas, Mulligan, Victoria M., Newman, Robert, Doyle, Kevin, Bürli, Roland, Barker, Daniel F., Glen, Angela, Ortuño, María José, Nectow, Alexander R., Renier, Nicolas, Cohen, Paul, Carlton, Mark, Heintz, Nathaniel, Friedman, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684079/
https://www.ncbi.nlm.nih.gov/pubmed/36411386
http://dx.doi.org/10.1038/s42255-022-00677-8