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Long noncoding RNA DIO3OS induces glycolytic-dominant metabolic reprogramming to promote aromatase inhibitor resistance in breast cancer

Aromatase inhibition is an efficient endocrine therapy to block ectopic estrogen production for postmenopausal estrogen receptor (ER)-positive breast cancer patients, but many develop resistance. Here, we show that aromatase inhibitor (AI)-resistant breast tumors display features of enhanced aerobic...

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Detalles Bibliográficos
Autores principales: Chen, Xueman, Luo, Rong, Zhang, Yunmei, Ye, Shuying, Zeng, Xin, Liu, Jiang, Huang, Di, Liu, Yujie, Liu, Qiang, Luo, Man-Li, Song, Erwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684133/
https://www.ncbi.nlm.nih.gov/pubmed/36418319
http://dx.doi.org/10.1038/s41467-022-34702-x