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Long noncoding RNA DIO3OS induces glycolytic-dominant metabolic reprogramming to promote aromatase inhibitor resistance in breast cancer
Aromatase inhibition is an efficient endocrine therapy to block ectopic estrogen production for postmenopausal estrogen receptor (ER)-positive breast cancer patients, but many develop resistance. Here, we show that aromatase inhibitor (AI)-resistant breast tumors display features of enhanced aerobic...
Autores principales: | Chen, Xueman, Luo, Rong, Zhang, Yunmei, Ye, Shuying, Zeng, Xin, Liu, Jiang, Huang, Di, Liu, Yujie, Liu, Qiang, Luo, Man-Li, Song, Erwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684133/ https://www.ncbi.nlm.nih.gov/pubmed/36418319 http://dx.doi.org/10.1038/s41467-022-34702-x |
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