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Computational modeling of complex bioenergetic mechanisms that modulate CD4+ T cell effector and regulatory functions

We built a computational model of complex mechanisms at the intersection of immunity and metabolism that regulate CD4+ T cell effector and regulatory functions by using coupled ordinary differential equations. The model provides an improved understanding of how CD4+ T cells are shaping the immune re...

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Detalles Bibliográficos
Autores principales: Baker, Ryan, Hontecillas, Raquel, Tubau-Juni, Nuria, Leber, Andrew J., Kale, Shiv, Bassaganya-Riera, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684137/
https://www.ncbi.nlm.nih.gov/pubmed/36418318
http://dx.doi.org/10.1038/s41540-022-00263-4