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Computational modeling of complex bioenergetic mechanisms that modulate CD4+ T cell effector and regulatory functions
We built a computational model of complex mechanisms at the intersection of immunity and metabolism that regulate CD4+ T cell effector and regulatory functions by using coupled ordinary differential equations. The model provides an improved understanding of how CD4+ T cells are shaping the immune re...
Autores principales: | Baker, Ryan, Hontecillas, Raquel, Tubau-Juni, Nuria, Leber, Andrew J., Kale, Shiv, Bassaganya-Riera, Josep |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684137/ https://www.ncbi.nlm.nih.gov/pubmed/36418318 http://dx.doi.org/10.1038/s41540-022-00263-4 |
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