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Efficient multitool/multiplex gene engineering with TALE-BE

TALE base editors are a recent addition to the genome editing toolbox. These molecular tools are fusions of a transcription activator-like effector domain (TALE), split-DddA deaminase halves, and an uracil glycosylase inhibitor (UGI) that have the distinct ability to directly edit double strand DNA,...

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Detalles Bibliográficos
Autores principales: Boyne, Alex, Yang, Ming, Pulicani, Sylvain, Feola, Maria, Tkach, Diane, Hong, Robert, Duclert, Aymeric, Duchateau, Philippe, Juillerat, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684181/
https://www.ncbi.nlm.nih.gov/pubmed/36440442
http://dx.doi.org/10.3389/fbioe.2022.1033669