Effects of tofacitinib therapy on arginine and methionine metabolites in association with vascular pathophysiology in rheumatoid arthritis: A metabolomic approach

INTRODUCTION: Rheumatoid arthritis (RA) has been associated with changes in lipid, arginine and NO metabolism with increased cardiovascular (CV) risk. The aim of this study is to evaluate the effect of tofacitinib, a Janus kinase (JAK) inhibitor, on arginine and methionine metabolism in correlation...

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Detalles Bibliográficos
Autores principales: Soós, Boglárka, Hamar, Attila, Pusztai, Anita, Czókolyová, Monika, Végh, Edit, Szamosi, Szilvia, Pethő, Zsófia, Gulyás, Katalin, Kerekes, György, Szántó, Sándor, Szűcs, Gabriella, Christians, Uwe, Klawitter, Jelena, Seres, Tamás, Szekanecz, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684209/
https://www.ncbi.nlm.nih.gov/pubmed/36438060
http://dx.doi.org/10.3389/fmed.2022.1011734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684209/
https://www.ncbi.nlm.nih.gov/pubmed/36438060
http://dx.doi.org/10.3389/fmed.2022.1011734

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