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Effect of inoculation with prion dilutions within the dynamic range of ELISA absorbance on prion incubation period

This study examines the effect of various infectious prion titers within the dynamic range as measured by ELISA on incubation period. We inoculated ovinized transgenic mice with seven decreasing dilutions of a fast-incubating scrapie strain. The highest inoculum group was a 20% w/v brain homogenate...

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Detalles Bibliográficos
Autores principales: Cassmann, Eric D., Brown, Quazetta L., Frese, Alexis J., Lambert, Zoe J., Greenlee, M. Heather West, Greenlee, Justin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684231/
https://www.ncbi.nlm.nih.gov/pubmed/36219301
http://dx.doi.org/10.1007/s11259-022-10013-w