Interleukin-1 Mediates Ischemic Brain Injury via Induction of IL-17A in γδ T Cells and CXCL1 in Astrocytes

As a prototypical proinflammatory cytokine, interleukin-1 (IL-1) exacerbates the early post-stroke inflammation, whereas its neutralization is protective. To further investigate the underlying cell-type-specific IL-1 effects, we subjected IL-1 (α/β) knockout (Il1(−/−)) and wildtype (WT) littermate m...

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Detalles Bibliográficos
Autores principales: Schädlich, Ines Sophie, Vienhues, Jonas Heinrich, Jander, Alina, Piepke, Marius, Magnus, Tim, Lambertsen, Kate Lykke, Clausen, Bettina Hjelm, Gelderblom, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684245/
https://www.ncbi.nlm.nih.gov/pubmed/35384588
http://dx.doi.org/10.1007/s12017-022-08709-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684245/
https://www.ncbi.nlm.nih.gov/pubmed/35384588
http://dx.doi.org/10.1007/s12017-022-08709-y

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