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CD11c regulates late-stage T cell development in the thymus

CD11c, also named integrin αX, has been deemed solely as a dendritic cell marker for decades while the delineation of its biological function was limited. In the current study, we observed in mice that CD11c deficiency led to a defect in T cell development, demonstrated by the loss of CD4(+)CD8(+) d...

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Detalles Bibliográficos
Autores principales: Hou, Lifei, Yuki, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684328/
https://www.ncbi.nlm.nih.gov/pubmed/36439108
http://dx.doi.org/10.3389/fimmu.2022.1040818