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Polymeric micelles effectively reprogram the tumor microenvironment to potentiate nano-immunotherapy in mouse breast cancer models

Nano-immunotherapy improves breast cancer outcomes but not all patients respond and none are cured. To improve efficacy, research focuses on drugs that reprogram cancer-associated fibroblasts (CAFs) to improve therapeutic delivery and immunostimulation. These drugs, however, have a narrow therapeuti...

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Detalles Bibliográficos
Autores principales: Panagi, Myrofora, Mpekris, Fotios, Chen, Pengwen, Voutouri, Chrysovalantis, Nakagawa, Yasuhiro, Martin, John D., Hiroi, Tetsuro, Hashimoto, Hiroko, Demetriou, Philippos, Pierides, Chryso, Samuel, Rekha, Stylianou, Andreas, Michael, Christina, Fukushima, Shigeto, Georgiou, Paraskevi, Papageorgis, Panagiotis, Papaphilippou, Petri Ch., Koumas, Laura, Costeas, Paul, Ishii, Genichiro, Kojima, Motohiro, Kataoka, Kazunori, Cabral, Horacio, Stylianopoulos, Triantafyllos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684407/
https://www.ncbi.nlm.nih.gov/pubmed/36418896
http://dx.doi.org/10.1038/s41467-022-34744-1