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Polymeric micelles effectively reprogram the tumor microenvironment to potentiate nano-immunotherapy in mouse breast cancer models
Nano-immunotherapy improves breast cancer outcomes but not all patients respond and none are cured. To improve efficacy, research focuses on drugs that reprogram cancer-associated fibroblasts (CAFs) to improve therapeutic delivery and immunostimulation. These drugs, however, have a narrow therapeuti...
Autores principales: | Panagi, Myrofora, Mpekris, Fotios, Chen, Pengwen, Voutouri, Chrysovalantis, Nakagawa, Yasuhiro, Martin, John D., Hiroi, Tetsuro, Hashimoto, Hiroko, Demetriou, Philippos, Pierides, Chryso, Samuel, Rekha, Stylianou, Andreas, Michael, Christina, Fukushima, Shigeto, Georgiou, Paraskevi, Papageorgis, Panagiotis, Papaphilippou, Petri Ch., Koumas, Laura, Costeas, Paul, Ishii, Genichiro, Kojima, Motohiro, Kataoka, Kazunori, Cabral, Horacio, Stylianopoulos, Triantafyllos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684407/ https://www.ncbi.nlm.nih.gov/pubmed/36418896 http://dx.doi.org/10.1038/s41467-022-34744-1 |
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