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TBX1 targets the miR-200–ZEB2 axis to induce epithelial differentiation and inhibit stem cell properties

TBX1, which encodes a T-box transcription factor, is considered a candidate gene for DiGeorge syndrome, velocardiofacial syndrome, and conotruncal anomaly face syndrome. Transduction of TBX1 decreases cell proliferation in epithelial cancer cells and Tbx1 ablation induces epithelial proliferation du...

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Detalles Bibliográficos
Autores principales: Funato, Noriko, Yanagisawa, Hiromi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684448/
https://www.ncbi.nlm.nih.gov/pubmed/36418889
http://dx.doi.org/10.1038/s41598-022-24604-9