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TBX1 targets the miR-200–ZEB2 axis to induce epithelial differentiation and inhibit stem cell properties
TBX1, which encodes a T-box transcription factor, is considered a candidate gene for DiGeorge syndrome, velocardiofacial syndrome, and conotruncal anomaly face syndrome. Transduction of TBX1 decreases cell proliferation in epithelial cancer cells and Tbx1 ablation induces epithelial proliferation du...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684448/ https://www.ncbi.nlm.nih.gov/pubmed/36418889 http://dx.doi.org/10.1038/s41598-022-24604-9 |