NetREX-CF integrates incomplete transcription factor data with gene expression to reconstruct gene regulatory networks

The inference of Gene Regulatory Networks (GRNs) is one of the key challenges in systems biology. Leading algorithms utilize, in addition to gene expression, prior knowledge such as Transcription Factor (TF) DNA binding motifs or results of TF binding experiments. However, such prior knowledge is ty...

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Detalles Bibliográficos
Autores principales: Wang, Yijie, Lee, Hangnoh, Fear, Justin M., Berger, Isabelle, Oliver, Brian, Przytycka, Teresa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684490/
https://www.ncbi.nlm.nih.gov/pubmed/36418514
http://dx.doi.org/10.1038/s42003-022-04226-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684490/
https://www.ncbi.nlm.nih.gov/pubmed/36418514
http://dx.doi.org/10.1038/s42003-022-04226-7

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