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NetREX-CF integrates incomplete transcription factor data with gene expression to reconstruct gene regulatory networks
The inference of Gene Regulatory Networks (GRNs) is one of the key challenges in systems biology. Leading algorithms utilize, in addition to gene expression, prior knowledge such as Transcription Factor (TF) DNA binding motifs or results of TF binding experiments. However, such prior knowledge is ty...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684490/ https://www.ncbi.nlm.nih.gov/pubmed/36418514 http://dx.doi.org/10.1038/s42003-022-04226-7 |