Construction of a synthetic methodology-based library and its application in identifying a GIT/PIX protein–protein interaction inhibitor

In recent years, the flourishing of synthetic methodology studies has provided concise access to numerous molecules with new chemical space. These compounds form a large library with unique scaffolds, but their application in hit discovery is not systematically evaluated. In this work, we establish...

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Detalles Bibliográficos
Autores principales: Gu, Jing, Peng, Rui-Kun, Guo, Chun-Ling, Zhang, Meng, Yang, Jie, Yan, Xiao, Zhou, Qian, Li, Hongwei, Wang, Na, Zhu, Jinwei, Ouyang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684509/
https://www.ncbi.nlm.nih.gov/pubmed/36418900
http://dx.doi.org/10.1038/s41467-022-34598-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684509/
https://www.ncbi.nlm.nih.gov/pubmed/36418900
http://dx.doi.org/10.1038/s41467-022-34598-7

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