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Construction of a synthetic methodology-based library and its application in identifying a GIT/PIX protein–protein interaction inhibitor
In recent years, the flourishing of synthetic methodology studies has provided concise access to numerous molecules with new chemical space. These compounds form a large library with unique scaffolds, but their application in hit discovery is not systematically evaluated. In this work, we establish...
Autores principales: | Gu, Jing, Peng, Rui-Kun, Guo, Chun-Ling, Zhang, Meng, Yang, Jie, Yan, Xiao, Zhou, Qian, Li, Hongwei, Wang, Na, Zhu, Jinwei, Ouyang, Qin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684509/ https://www.ncbi.nlm.nih.gov/pubmed/36418900 http://dx.doi.org/10.1038/s41467-022-34598-7 |
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