Inflammatory bone marrow signaling in pediatric acute myeloid leukemia distinguishes patients with poor outcomes

High levels of the inflammatory cytokine IL-6 in the bone marrow are associated with poor outcomes in pediatric acute myeloid leukemia (pAML), but its etiology remains unknown. Using RNA-seq data from pre-treatment bone marrows of 1489 children with pAML, we show that > 20% of patients have concu...

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Detalles Bibliográficos
Autores principales: Bolouri, Hamid, Ries, Rhonda E., Wiedeman, Alice E., Hylkema, Tiffany, Scheiding, Sheila, Gersuk, Vivian H., O’Brien, Kimberly, Nguyen, Quynh-Anh, Smith, Jenny L., Alice Long, S., Meshinchi, Soheil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684530/
https://www.ncbi.nlm.nih.gov/pubmed/36418348
http://dx.doi.org/10.1038/s41467-022-34965-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684530/
https://www.ncbi.nlm.nih.gov/pubmed/36418348
http://dx.doi.org/10.1038/s41467-022-34965-4

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