Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice

Hemophilia A is an X-linked recessive congenital bleeding disorder. Exogenous infusion of FVIII is the treatment of choice, and the development of immunoglobulins against FVIII (inhibitors) remains the major challenge in clinical management of the disease. Here, we investigated the effect of co-admi...

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Detalles Bibliográficos
Autores principales: Afraz, Sajjad, Stevic, Ivan, Matino, Davide, Wen, Jianping, Atkinson, Helen, Chan, Anthony K. C., Hortelano, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684572/
https://www.ncbi.nlm.nih.gov/pubmed/36418333
http://dx.doi.org/10.1038/s41598-022-19392-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684572/
https://www.ncbi.nlm.nih.gov/pubmed/36418333
http://dx.doi.org/10.1038/s41598-022-19392-1

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