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Spliceosomal profiling identifies EIF4A3 as a novel oncogene in hepatocellular carcinoma acting through the modulation of FGFR4 splicing

INTRODUCTION: Altered splicing landscape is an emerging cancer hallmark; however, the dysregulation and implication of the cellular machinery controlling this process (spliceosome components and splicing factors) in hepatocellular carcinoma (HCC) is poorly known. This study aimed to comprehensively...

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Detalles Bibliográficos
Autores principales: López‐Cánovas, Juan L., Hermán‐Sánchez, Natalia, Moreno‐Montilla, Maria Trinidad, del Rio‐Moreno, Mercedes, Alors‐Perez, Emilia, Sánchez‐Frias, Marina E., Amado, Víctor, Ciria, Rubén, Briceño, Javier, de la Mata, Manuel, Castaño, Justo P., Rodriguez‐Perálvarez, Manuel, Luque, Raúl M., Gahete, Manuel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684617/
https://www.ncbi.nlm.nih.gov/pubmed/36419260
http://dx.doi.org/10.1002/ctm2.1102