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Plasma cell but not CD20-mediated B-cell depletion protects from bleomycin-induced lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease associated with chronic inflammation and tissue remodelling leading to fibrosis, reduced pulmonary function, respiratory failure and death. Bleomycin (Blm)-induced lung fibrosis in mice replicates several clinical features of human...

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Detalles Bibliográficos
Autores principales: Prêle, Cecilia M., Miles, Tylah, Pearce, David R., O'Donoghue, Robert J., Grainge, Chris, Barrett, Lucy, Birnie, Kimberly, Lucas, Andrew D., Baltic, Svetlana, Ernst, Matthias, Rinaldi, Catherine, Laurent, Geoffrey J., Knight, Darryl A., Fear, Mark, Hoyne, Gerard, McAnulty, Robin J., Mutsaers, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684624/
https://www.ncbi.nlm.nih.gov/pubmed/35798357
http://dx.doi.org/10.1183/13993003.01469-2021