Terfenadine resensitizes doxorubicin activity in drug-resistant ovarian cancer cells via an inhibition of CaMKII/CREB1 mediated ABCB1 expression

Ovarian cancer is one of the most lethal gynecological malignancies. Recurrence or acquired chemoresistance is the leading cause of ovarian cancer therapy failure. Overexpression of ATP-binding cassette subfamily B member 1 (ABCB1), commonly known as P-glycoprotein, correlates closely with multidrug...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Yang, Shu, Cheng, Yu-Shan, Sima, Ni, Sun, Wei, Shen, Min, Braisted, John C., Lu, Weiguo, Zheng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684669/
https://www.ncbi.nlm.nih.gov/pubmed/36439493
http://dx.doi.org/10.3389/fonc.2022.1068443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684669/
https://www.ncbi.nlm.nih.gov/pubmed/36439493
http://dx.doi.org/10.3389/fonc.2022.1068443

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