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Biophysical studies of amorphous protein aggregation and in vivo immunogenicity
Amorphous protein aggregates are oligomers that lack specific, high-order structures. Soluble amorphous aggregates are smaller than ~1 µm. Despite their lack of high-order structure, amorphous protein aggregates exhibit specific biophysical properties such as reversibility of formation, density, con...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684872/ https://www.ncbi.nlm.nih.gov/pubmed/36465085 http://dx.doi.org/10.1007/s12551-022-01011-y |