Genome-wide screening for genetic variants in polyadenylation signal (PAS) sites in mouse selection lines for fatness and leanness

Alternative polyadenylation (APA) determines mRNA stability, localisation, translation and protein function. Several diseases, including obesity, have been linked to APA. Studies have shown that single nucleotide polymorphisms in polyadenylation signals (PAS-SNPs) can influence APA and affect phenot...

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Detalles Bibliográficos
Autores principales: Šimon, Martin, Mikec, Špela, Morton, Nicholas M., Atanur, Santosh S., Konc, Janez, Horvat, Simon, Kunej, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684942/
https://www.ncbi.nlm.nih.gov/pubmed/36414820
http://dx.doi.org/10.1007/s00335-022-09967-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684942/
https://www.ncbi.nlm.nih.gov/pubmed/36414820
http://dx.doi.org/10.1007/s00335-022-09967-8

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