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The genetic and biochemical determinants of mRNA degradation rates in mammals

BACKGROUND: Degradation rate is a fundamental aspect of mRNA metabolism, and the factors governing it remain poorly characterized. Understanding the genetic and biochemical determinants of mRNA half-life would enable more precise identification of variants that perturb gene expression through post-t...

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Detalles Bibliográficos
Autores principales: Agarwal, Vikram, Kelley, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684954/
https://www.ncbi.nlm.nih.gov/pubmed/36419176
http://dx.doi.org/10.1186/s13059-022-02811-x