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Higher body mass index is associated with a lower iloprost infusion rate tolerance and higher iloprost-related adverse events in patients with systemic sclerosis

BACKGROUND: Systemic sclerosis (SSc) is an autoimmune disease characterized by vasospasm and microvascular involvement. Iloprost (ILO), a prostaglandin analogous, is used for the treatment of SSc-related Raynaud’s phenomenon and digital ulcers. The suggested dose is 0.5–2 ng/kg/min for 6–8 h, and th...

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Detalles Bibliográficos
Autores principales: Bixio, Riccardo, Adami, Giovanni, Bertoldo, Eugenia, Giollo, Alessandro, Morciano, Andrea, Bertelle, Davide, Orsolini, Giovanni, Idolazzi, Luca, Rossini, Maurizio, Viapiana, Ombretta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685102/
https://www.ncbi.nlm.nih.gov/pubmed/36439640
http://dx.doi.org/10.1177/1759720X221137125