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CRISPR nuclease off-target activity and mitigation strategies
The discovery of CRISPR has allowed site-specific genomic modification to become a reality and this technology is now being applied in a number of human clinical trials. While this technology has demonstrated impressive efficacy in the clinic to date, there remains the potential for unintended on- a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685173/ https://www.ncbi.nlm.nih.gov/pubmed/36439866 http://dx.doi.org/10.3389/fgeed.2022.1050507 |