SIRT1 activation attenuates microglia-mediated synaptic engulfment in postoperative cognitive dysfunction

BACKGROUND: Postoperative cognitive dysfunction (POCD) is a debilitating neurological complication in surgical patients. Current research has focused mainly on microglial activation, but less is known about the resultant neuronal synaptic changes. Recent studies have suggested that Sirtuin-1 (SIRT1)...

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Detalles Bibliográficos
Autores principales: Sun, Yi, Wang, Yuzhu, Ye, Fan, Cui, Victoria, Lin, Dandan, Shi, Hui, Zhang, Yan, Wu, Anshi, Wei, Changwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685341/
https://www.ncbi.nlm.nih.gov/pubmed/36437988
http://dx.doi.org/10.3389/fnagi.2022.943842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685341/
https://www.ncbi.nlm.nih.gov/pubmed/36437988
http://dx.doi.org/10.3389/fnagi.2022.943842

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