2,4-Disubstituted pyridine derivatives are effective against intracellular and biofilm-forming tubercle bacilli

It was recently reported that 4-substituted picolinohydrazonamides carrying hydrophilic cyclic amines, such as morpholine and pyrrolidine, at the end of their thiosemicarbazide chain have potent antimycobacterial activity in vitro at concentrations below 1 μg/ml. Here, two selected compounds, 2,4-di...

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Detalles Bibliográficos
Autores principales: Korycka-Machała, M., Kawka, M., Lach, J., Płocińska, R., Bekier, A., Dziadek, B., Brzostek, A., Płociński, P., Strapagiel, D., Szczesio, M., Gobis, K., Dziadek, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685343/
https://www.ncbi.nlm.nih.gov/pubmed/36438838
http://dx.doi.org/10.3389/fphar.2022.1004632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685343/
https://www.ncbi.nlm.nih.gov/pubmed/36438838
http://dx.doi.org/10.3389/fphar.2022.1004632

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