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AJUBA and WTIP can compete with LIMD1 for junctional localization and LATS regulation

Each of the three mammalian Ajuba family proteins, AJUBA, LIMD1 and WTIP, exhibit tension-dependent localization to adherens junctions, and can associate with Lats kinases. However, only LIMD1 has been directly demonstrated to directly regulate Lats activity in vivo. To assess the relationship of LI...

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Detalles Bibliográficos
Autores principales: Kirichenko, Elmira, Irvine, Kenneth D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685415/
https://www.ncbi.nlm.nih.gov/pubmed/36439396
http://dx.doi.org/10.17912/micropub.biology.000666