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Nanoneedles Induce Targeted siRNA Silencing of p16 in the Human Corneal Endothelium

Nanoneedles can target nucleic acid transfection to primary cells at tissue interfaces with high efficiency and minimal perturbation. The corneal endothelium is an ideal target for nanoneedle‐mediated RNA interference therapy aimed at enhancing its proliferative capacity, necessary for tissue regene...

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Detalles Bibliográficos
Autores principales: Maurizi, Eleonora, Martella, Davide Alessandro, Schiroli, Davide, Merra, Alessia, Mustfa, Salman Ahmad, Pellegrini, Graziella, Macaluso, Claudio, Chiappini, Ciro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685449/
https://www.ncbi.nlm.nih.gov/pubmed/36253148
http://dx.doi.org/10.1002/advs.202203257