Outward Movement of Targeting Ligands from a Built‐In Reserve Pool in Nuclease‐Resistant 3D Hierarchical DNA Nanocluster for in Vivo High‐Precision Cancer Therapy

Nanostructures made entirely of DNAs display great potential as chemotherapeutic drug carriers but so far cannot achieve sufficient clinic therapy outcomes due to off‐target toxicity. In this contribution, an aptamer‐embedded hierarchical DNA nanocluster (Apt‐eNC) is constructed as an intelligent ca...

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Detalles Bibliográficos
Autores principales: Wang, Weijun, Gao, Yansha, Chen, Yaxin, Wang, Wenqing, Li, Qian, Huang, Zhiyi, Zhang, Jingjing, Xiang, Qi, Wu, Zai‐Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685459/
https://www.ncbi.nlm.nih.gov/pubmed/36253152
http://dx.doi.org/10.1002/advs.202203698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685459/
https://www.ncbi.nlm.nih.gov/pubmed/36253152
http://dx.doi.org/10.1002/advs.202203698

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