Fast and Ultrasensitive Glycoform Analysis by Supercritical Fluid Chromatography–Tandem Mass Spectrometry

[Image: see text] The glycoform of a therapeutic monoclonal antibody (mAb) has a significant impact on its effector function as well as its safety and pharmacokinetics. Glycoform heterogeneity is influenced by various factors, including the producing cells and cell culture processes. Therefore, accu...

Descripción completa

Detalles Bibliográficos
Autores principales: Haga, Yoshimi, Yamada, Masaki, Fujii, Risa, Saichi, Naomi, Yokokawa, Takashi, Hama, Toshihiro, Hayakawa, Yoshihiro, Ueda, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685587/
https://www.ncbi.nlm.nih.gov/pubmed/36345688
http://dx.doi.org/10.1021/acs.analchem.2c01721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685587/
https://www.ncbi.nlm.nih.gov/pubmed/36345688
http://dx.doi.org/10.1021/acs.analchem.2c01721

Ejemplares similares