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Fast and Ultrasensitive Glycoform Analysis by Supercritical Fluid Chromatography–Tandem Mass Spectrometry

[Image: see text] The glycoform of a therapeutic monoclonal antibody (mAb) has a significant impact on its effector function as well as its safety and pharmacokinetics. Glycoform heterogeneity is influenced by various factors, including the producing cells and cell culture processes. Therefore, accu...

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Detalles Bibliográficos
Autores principales:	Haga, Yoshimi, Yamada, Masaki, Fujii, Risa, Saichi, Naomi, Yokokawa, Takashi, Hama, Toshihiro, Hayakawa, Yoshihiro, Ueda, Koji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685587/ https://www.ncbi.nlm.nih.gov/pubmed/36345688 http://dx.doi.org/10.1021/acs.analchem.2c01721

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