Improved Subcutaneous Delivery of Ketoconazole Using EpiDerm and HSPiP Software-Based Simulations as Assessed by Cell Viability, Cellular Uptake, Permeation, and Hemolysis In Vitro Studies

[Image: see text] Ketoconazole (KETO) is the drug of choice to control local, systemic, and resistant types of fungal infections. Subcutaneous (sub-Q) delivery offers several benefits. The present study investigated the sub-Q delivery of KETO using HSPiP software based on optimized concentrations of...

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Detalles Bibliográficos
Autores principales: Hussain, Afzal, Afzal, Obaid, Altamimi, Mohammad A., Alfawaz Altamimi, Abdulmalik Saleh, Ramzan, Mohhammad, Hassan, Mohd. Zaheen, Mahdi, Wael A., Webster, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685774/
https://www.ncbi.nlm.nih.gov/pubmed/36440147
http://dx.doi.org/10.1021/acsomega.2c06001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685774/
https://www.ncbi.nlm.nih.gov/pubmed/36440147
http://dx.doi.org/10.1021/acsomega.2c06001

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