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Improved Subcutaneous Delivery of Ketoconazole Using EpiDerm and HSPiP Software-Based Simulations as Assessed by Cell Viability, Cellular Uptake, Permeation, and Hemolysis In Vitro Studies
[Image: see text] Ketoconazole (KETO) is the drug of choice to control local, systemic, and resistant types of fungal infections. Subcutaneous (sub-Q) delivery offers several benefits. The present study investigated the sub-Q delivery of KETO using HSPiP software based on optimized concentrations of...
Autores principales: | Hussain, Afzal, Afzal, Obaid, Altamimi, Mohammad A., Alfawaz Altamimi, Abdulmalik Saleh, Ramzan, Mohhammad, Hassan, Mohd. Zaheen, Mahdi, Wael A., Webster, Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685774/ https://www.ncbi.nlm.nih.gov/pubmed/36440147 http://dx.doi.org/10.1021/acsomega.2c06001 |
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