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Lactobacillus reuteri tryptophan metabolism promotes host susceptibility to CNS autoimmunity

BACKGROUND: Dysregulation of gut microbiota-associated tryptophan metabolism has been observed in patients with multiple sclerosis. However, defining direct mechanistic links between this apparent metabolic rewiring and individual constituents of the gut microbiota remains challenging. We and others...

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Detalles Bibliográficos
Autores principales: Montgomery, Theresa L., Eckstrom, Korin, Lile, Katarina H., Caldwell, Sydney, Heney, Eamonn R., Lahue, Karolyn G., D’Alessandro, Angelo, Wargo, Matthew J., Krementsov, Dimitry N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685921/
https://www.ncbi.nlm.nih.gov/pubmed/36419205
http://dx.doi.org/10.1186/s40168-022-01408-7