Whole-exome sequencing of BRCA-negative breast cancer patients and case–control analyses identify variants associated with breast cancer susceptibility

BACKGROUND: For the majority of individuals with early-onset or familial breast cancer referred for genetic testing, the genetic basis of their familial breast cancer remains unexplained. To identify novel germline variants associated with breast cancer predisposition, whole-exome sequencing (WES) w...

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Detalles Bibliográficos
Autores principales: Lee, Ning Yuan, Hum, Melissa, Amali, Aseervatham Anusha, Lim, Wei Kiat, Wong, Matthew, Myint, Matthew Khine, Tay, Ru Jin, Ong, Pei-Yi, Samol, Jens, Lim, Chia Wei, Ang, Peter, Tan, Min-Han, Lee, Soo-Chin, Lee, Ann S. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685974/
https://www.ncbi.nlm.nih.gov/pubmed/36424660
http://dx.doi.org/10.1186/s40246-022-00435-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685974/
https://www.ncbi.nlm.nih.gov/pubmed/36424660
http://dx.doi.org/10.1186/s40246-022-00435-7

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