A peptoid interleukin‐15 receptor antagonist suppresses inflammation and arthritis in mice

OBJECTIVE: To discover a novel peptoid antagonist that targets the interleukin‐15 (IL‐15) receptor and to evaluate its therapeutic efficacy in the treatment of inflammation and arthritis. METHODS: A new compound (IFRA3, interleukin‐15 receptor antagonist 3) was discovered using a unique on‐bead two‐...

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Detalles Bibliográficos
Autores principales: Cho, Kwang Bog, Shukla, Satya Prakash, Kannan, Maheshkumar, Zhang, Haowen, Amina, Sundus Jabeen, Zhou, Shuang, Chen, Yanping, Molligan, Jeremiah F, Taneja, Veena, Mohan, Chandra, Udugamasooriya, D Gomika, Guo, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686008/
https://www.ncbi.nlm.nih.gov/pubmed/36439637
http://dx.doi.org/10.1002/cti2.1432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686008/
https://www.ncbi.nlm.nih.gov/pubmed/36439637
http://dx.doi.org/10.1002/cti2.1432

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