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A peptoid interleukin‐15 receptor antagonist suppresses inflammation and arthritis in mice
OBJECTIVE: To discover a novel peptoid antagonist that targets the interleukin‐15 (IL‐15) receptor and to evaluate its therapeutic efficacy in the treatment of inflammation and arthritis. METHODS: A new compound (IFRA3, interleukin‐15 receptor antagonist 3) was discovered using a unique on‐bead two‐...
Autores principales: | Cho, Kwang Bog, Shukla, Satya Prakash, Kannan, Maheshkumar, Zhang, Haowen, Amina, Sundus Jabeen, Zhou, Shuang, Chen, Yanping, Molligan, Jeremiah F, Taneja, Veena, Mohan, Chandra, Udugamasooriya, D Gomika, Guo, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686008/ https://www.ncbi.nlm.nih.gov/pubmed/36439637 http://dx.doi.org/10.1002/cti2.1432 |
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