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Time-course RNA-Seq profiling reveals isoform-level gene expression dynamics of the cGAS-STING pathway

The cGAS-STING pathway, orchestrating complicated transcriptome-wide immune responses, is essential for host antiviral defense but can also drive immunopathology in severe COVID-19. Here, we performed time-course RNA-Seq experiments to dissect the transcriptome expression dynamics at the gene-isofor...

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Detalles Bibliográficos
Autores principales: Sun, Jing, Li, Lu, Hu, Jiameng, Gao, Yan, Song, Jinyi, Zhang, Xiang, Hu, Haiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686058/
https://www.ncbi.nlm.nih.gov/pubmed/36448027
http://dx.doi.org/10.1016/j.csbj.2022.11.044