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Mediating oxidative stress enhances α-ionone biosynthesis and strain robustness during process scaling up

BACKGROUND: α-Ionone is highly valued in cosmetics and perfumery with a global usage of 100–1000 tons per year. Metabolic engineering by microbial fermentation offers a promising way to produce natural (R)-α-ionone in a cost-effective manner. Apart from optimizing the metabolic pathways, the approac...

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Detalles Bibliográficos
Autores principales: Huang, Ching-Ning, Lim, Xiaohui, Ong, Leonard, Lim, Chinchin, Chen, Xixian, Zhang, Congqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686065/
https://www.ncbi.nlm.nih.gov/pubmed/36424649
http://dx.doi.org/10.1186/s12934-022-01968-1