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The prognostic significance of CXCR4 and SDF-1 in differentiated thyroid cancer depends on CD8+ density

BACKGROUND: Tumor infiltration with cytotoxic CD8+ T-cells is associated with a favorable outcome in several neoplasms, including thyroid cancer. The chemokine axis CXCR4/SDF-1 correlates with more aggressive tumors, but little is known concerning the prognostic relevance in relation to the tumor im...

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Detalles Bibliográficos
Autores principales: Wilhelm, Alexander, Lemmenmeier, Isabelle, Lalos, Alexandros, Posabella, Alberto, Kancherla, Venkatesh, Piscuoglio, Salvatore, Delko, Tarik, von Flüe, Markus, Glatz, Kathrin, Droeser, Raoul André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686066/
https://www.ncbi.nlm.nih.gov/pubmed/36419107
http://dx.doi.org/10.1186/s12902-022-01204-2