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The prognostic significance of CXCR4 and SDF-1 in differentiated thyroid cancer depends on CD8+ density
BACKGROUND: Tumor infiltration with cytotoxic CD8+ T-cells is associated with a favorable outcome in several neoplasms, including thyroid cancer. The chemokine axis CXCR4/SDF-1 correlates with more aggressive tumors, but little is known concerning the prognostic relevance in relation to the tumor im...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686066/ https://www.ncbi.nlm.nih.gov/pubmed/36419107 http://dx.doi.org/10.1186/s12902-022-01204-2 |